Dr.NISHAT AFROZE*, Dr.MOHAMMAD IBRAHIM.SHAIK, Dr.SHAIK JAFFAR Leucorrhoea, Gynaecology, Candida, Gardenella vaginalis. 1464-1478 Volume 4, Issue 6 November - December 2013 Leucorrhoea or vaginal discharge is one of the very common problems or complaints among females of reproductive age group (15 yrs. - 45yrs.) attending to Gynaecology and Veneriology outpatient department .Leucorrhoea or vaginal discharge constitute a considerable problem for many women causing discomfort, anxiety affecting womens quality of life and consuming considerable resources. The aim of the present study to isolation, identification and to assess the frequency of occurrence of various microbial agents in patients with leucorrhoea attending to Gynaecology,obstetrics and Veneriology, outpatient departments in Owisi Hospital, Hyderabad. This study helps to assess the role of microorganisms in causation of leucorrhoeas. It helps the clinician to give proper treatment and better patient care in this era of antibiotic resistance and immuno deficiency.