• ISSN : 2231 - 0541 (Online)
  • 0976 - 3090 (print)
  • NLM ID : 101613942
  • CAS CODEN : PHARN8
  • Frequency : Bi-Monthly

PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF VARIOUS SOLVENT EXTRACTS OF PUNICA GRANATUM AND PHYLLANTHUS NIRURI

PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF VARIOUS SOLVENT EXTRACTS OF PUNICA GRANATUM AND PHYLLANTHUS NIRURI

The development of antimicrobial drugs or antibiotics is major challenge in the growing world because long term usage of commercially available drugs to treatment of various microbial diseases, after prolonged use of synthetic drugs may be pathogens get resistance from that particular synthetic drugs and also have their adverse effects, so alternative strategies are to develop the effective drugs from traditional medicine The aim of the present study to evaluate the antimicrobial activity of Punica granatum peels and whole plant of phyllanthus niruri extracts such as low polar to high polar solvent extracts. In folk medicine peels of Punica granatum and whole plant of phyllanthus niruri has been commonly used for treatment of various ailments like diarrhea, various infectious diseases. Aqueous, methanolic and ethanolic extracts of Punica granatum peels and whole plant of phyllanthus niruri show an average inhibitory zone diameter of 12,14,16mm respectively which indicates that ethanolic extract shows best result having ZOI greater than that of the standard antibiotics ampcillin is 14 mm. Mehanolic extract of Punica Granatum and whole plant of phyllanthus niruri has lowest MIC of 1.45,1.36?g/ml showing that it is most effective as compared to MICs of other extracts.