• ISSN : 2231 - 0541 (Online)
  • 0976 - 3090 (print)
  • NLM ID : 101613942
  • CAS CODEN : PHARN8
  • Frequency : Bi-Monthly

OVULATION INDUCING AND FOLLICULOGENETIC ACTIVITY OF UPPU PARPA IN FEMALE WISTAR ALBINO RATS

OVULATION INDUCING AND FOLLICULOGENETIC ACTIVITY OF UPPU PARPA IN FEMALE WISTAR ALBINO RATS

This study has been undertaken to investigate the effect of Uppu parpa on folliculogenesis, relative ovary and uterus weight and number of ovarian surface follicles in female Wistar albino rats. The study consisted of 6 female wistar rats in a group and totally 24 rats were taken. Group-I was given 2ml/kg of CMC solution, Group II and III were received 50mg and 100mg of Uppu parpa respectively and group IV received Clomiphene citrate 10mg/kg body weight and it is considered as standard. After 10 days, blood samples were taken from all groups in order to measure the serum levels of luteinizing hormone (LH), follicle stimulating hormone (FSH) and estradiol hormones. Ovaries and uterus were removed for histopathology studies. Significant increase in FSH, LH and estradiol levels, ovarian and uterine weight was noticed along with increased folliculogenesis in the experimental groups. Thus the results suggested the significant ovulatory response in female rats, and can be used clinically in reproductive hormonal disorders and in infertility condition of female.