• ISSN : 2231 - 0541 (Online)
  • 0976 - 3090 (print)
  • NLM ID : 101613942
  • CAS CODEN : PHARN8
  • Frequency : Bi-Monthly

BENZOTHIAZOLE - A POTENT PHARMACOPHORE IN MEDICINAL CHEMISTRY: A REVIEW

BENZOTHIAZOLE - A POTENT PHARMACOPHORE IN MEDICINAL CHEMISTRY: A REVIEW

Benzoheterocycles such as benzothiazoles, benzimidazoles and benzoxazoles can serve as unique and versatile scaffolds for experimental drug design. Among the all Benzoheterocycles,
benzothiazole has considerable place in research area especially in synthetic as well as in pharmaceutical chemistry because of its potent and significant pharmacological activities. Since, a wide range of methods are available for synthesizing benzothiazole nucleus and its derivatives but a real need exists for new procedures that support many kinds of structural diversity and various
substitution. The present review deals with the common methods adopted and reported to focus the synthesis as well as cyclisation of benzothiazole nucleus.